"We have said we need the leadership in sport to raise their voice against this pandemic. Therefore, they will continue with their matches without spectators and finish the season," Mthethwa said.
"The most important thing is that as they do that [continue playing] they will be spreading the message to fight against this pandemic. as we speak they can have their matches with no spectators.
"Their obligation is to follow the health and hygiene protocols to the letter."
Fans were left bemused after the highly anticipated match between Mamelodi Sundowns and Orlando Pirates, which was supposed to be played last night, was called off. Kaizer Chiefs were also meant to face Bidvest Wits tonight.
The PSL will convene a board of governors [BoG] meeting in Kempton Park tomorrow where club owners will map a way forward. It now looks likely that matches will be rescheduled and fixtures could resume next week with no fans at the stadium.
There are around eight league games left in the season while in the Nedbank Cup
only three games remain to be played (the semis and final).
Earlier in the week, Khoza said the PSL was prepared for any eventuality.
"We want our strategy to be in-sync with the government so that we don't do things differently. Then we will have
options as BoG to take a decision in the best interest of the country," he said.