Cosatu and Sanco in Gauteng have led the calls for Masuku to take special leave.
Mapaila said they held the same view as Cosatu that Masuku must step aside.
"Of course this has been our general posture that in areas where there's a possibility of corruption that has arisen, the leadership can talk to the comrade and have a sense of how close that person was to that particular crisis.
"In that regard we would have no different opinion from that of Cosatu on this one," Mapaila said.
"But we are simply saying the people who are directly involved must be dealt with."
ANC treasurer-general Paul Mashatile said that ANC leaders should emulate the values of the late Struggle stalwart Andrew Mlangeni of serving with integrity.
"We must be able to make sure the ANC is an organisation that people can love and respect.
"When there are people within our midst who are... involved in corruption we must act against them," Mashatile said.
Royal Bhaca Projects, a company owned by Bhaca king Madzikazi II Thandisizwe, was awarded the multi-million-rand PPE tender by the Gauteng department of health.
Both Diko and Masuku have denied any wrongdoing in the matter.
Masuku said in a statement on Sunday that he had personally requested a forensic audit into Covid-19 procurement.
An ANC NEC member who asked not to be named told Sowetan yesterday that "heads must roll".
"For now we are leaving it to the ANC in the province and they announce on Thursday but if that decision is not satisfactory then we as the NEC will make a pronouncement at the meeting this weekend," said the member.
The ANC NEC member said he believed President Cyril Ramaphosa and premier David Makhura should have acted quickly and with more rigour when the allegations emerged.