They will need to win that game if they are to keep their chances of winning the league alive, and the 30-year-old defender admitted that those two games in hand will mean nothing if they don't win them.
"We had four (games in hand) at some point but we didn't take the points. I just feel we need to take each game as it comes."
With Leopards fighting for survival, Mkhwanazi expects them to come out and fight. "It won't be easy, they will be motivated playing against us who are trying to fight for the league and secondly, they are playing to survive relegation. I feel like they will come here and will be well prepared and fired up for this match."
Having failed to find the back of the net in their last two matches, the Bafana defender feels they have been unlucky not to win matches.
"When we play away we dominate but we mostly fail to take the chances we create."