"I call them a well-rested team and they should be able to compete for the league. They play every next [other] Saturday, so they have the energy and time to fix their problems.
"We [Sundowns] have to play every three days. They are the favourites, for me."
Rival fans of Chiefs have been up in arms because of what is seen as favourable officiating from referees during games.
"When it's Chiefs it's always a penalty. I must also benefit if Chiefs is benefitting from mistakes of the referees," Mosimane quipped in a post-match interview.
The well-oiled Brazilians are not too far adrift of the leaders in this early stage of the race. Sundowns have two games in hand and are five points behind with 14 points.
The African giants cruised to a 2-1 win over Black Leopards at the intimidating Thohoyandou Stadium in midweek.
"It is good to have an away win and also to catch up with our games in hand," Mosimane said.
"It's a difficult place to come and win [Venda] but we were able to take our chances."