Community members around Mbombela, Barberton, Matsulu, Ngodini and surrounding areas joined the protest, saying a petrol price increase triggers food price increases.
Blocked roads include Kaapschehoop, the N4 from Matsulu and Malalane, the R40 from Barberton and Lydenburg, KaBokweni and small roads in the Mbombela CBD.
Police spokesperson Brig Selvy Mohlala said at least eight people have been arrested.
“For now the Nelspruit CBD seems calm but we are moving to other areas, KaNyamazane, Emkhatsini and more. We have arrested eight suspects on charges of public disturbance and public violence, they are being processed as we speak,” said Mohlala.