"We are pleased to announce that in the early hours of tomorrow [Monday] a delegation of 217 Cuban Medical Brigade will arrive in South Africa," said the ministry.
"Some of these highly skilled health professionals were in the frontline of fighting other outbreaks in the world such as Cholera in Haiti in 2010, and Ebola in West Africa in 2013.
"Before departure from Cuba, the medical brigade had been placed in quarantine to ensure that they minimise any form of exposure prior to coming to South Africa."
The Cuban team will be placed in precautionary quarantine as they await their test results once in South Africa.
"We will also use this period to fully induct them into the South African situational analysis and the various provinces they will be deployed to," said the ministry.