Although Lesia trained as a family practitioner, she also studied health management which prepared her for administrative roles within the sector.
She worked at various public facilities, including the Leratong and Dr George Mukhari hospitals before joining her late husband in private practice in 1991.
"While I was in private practice I started studying management because I think deep down I've always wanted to serve in the public sector. I think at heart I'm a public servant," Lesia said.
In 2007, Lesia joined Chris Hani Baragwanath Academic Hospital and was appointed the hospital's clinical director in 2010.
She recalled the first day at the hospital after she was initially appointed.
"There was a big protest and it was really chaotic with people singing everywhere. I was thrown in the deep end," she said.
Lesia said she came to love and appreciate working at the hospital until she was appointed CEO of the Far East Rand Hospital in 2015.
She is, however, aware that going back to Baragwanath to tackle a much bigger role than before would require a lot from her. Her role also entails being in charge of the cluster of smaller hospitals which refer patients to the facility.
"Bara is the people's hospital. I believe it can be a beautiful place to work," she said.
Lesia is coming into the position after the hospital's previous acting CEO Dr Sifiso Maseko stepped down in August following allegations of mismanagement and corruption.
She said her first priority was to change the internal relations and inspire staff morale.
She believes that without good working relationships, the hospital cannot function properly.
She also wants to educate the community about how the hospital operates in order to reduce the waiting periods.
Lesia said people often bypass clinics and come to the hospital for minor conditions such as headaches, resulting in unnecessarily long queues.
She is also excited about being part of the latest developments in the health sector such as the implementation of the National Health Insurance (NHI).
"I see the need for NHI. We are struggling with budgets for resources in the public sector while there are resources in the private sector that are under-utilised.
"We need to expand," she said.