In March 2015, Tete poleaxed English star Paul Butler in the eighth round to register the first defence of his IBF junior bantamweight belt in Liverpool.
The promise of another breathtaking show was made yesterday by accomplished trainer Loyiso Mtya, who will be barking instructions to the former undefeated IBF champion.
Tete and Villanueva, both 28 years old, are rated No 2 and 1, respectively.
The winner will earn the rights to challenge current WBO bantamweight champion Marlon Tapales from the Philippines.
"Zolani will prove to the whole world that he is the best in the world pound for pound in the bantamweight division. People must expect a rounded Zolani," said Mtya.
He respects Villanueva as a "very good boxer who can be both aggressive and rough when he wants to".
He said Tete has been sparring with ABU junior featherweight champion Ludumo Lamati as part of his preparations.
"But we began sparring with Warren Joubert [SA junior welterweight champ] and two good amateurs from the gym of Colin Nathan on Tuesday. We are so ready."
Tete has 20 knockouts from 24 wins against three losses, while Villanueva, a former IBF junior bantamweight champion, has knocked out 16 of his 30 victims, losing once.