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The two teams have had some exciting cup match-ups against each other.
Pirates, who most recently beat Free State Stars 4-2 in the semifinals of this competition last year at Goble Park, were once again pitted against Ea Lla Koto in Thursday night’s draw held at the studios of Pay-TV sports channel SuperSport in Randburg.
None of South Africa’s big three were drawn against each other in the last-16 matches to be played from April 5 to 8.
Kaizer Chiefs will travel to Nelspruit to meet Acornbush United, one of two ABC Motsepe League (third division) teams left in the competition, who beat Cape Town City in the last-32.
Mamelodi Sundowns are at home to fellow Premier League team Lamontville Golden Arrows.
The exact venues and dates are to be announced.
Nedbank Cup last-16 (home teams first, venues to be announced):
Chippa United v Polokwane City
KwaDukuza United v SuperSport United
Bloemfontein Celtic v Mbombela United
Free State Stars v Orlando Pirates
Jomo Cosmos v Bidvest Wits
Baroka FC v Platinum Stars
Mamelodi Sundowns v Lamontville Golden Arrows
Acornbush United v Kaizer Chiefs
- TMG Digital/TMG Sport