THE IFP is determined to persist in its opposition to the eThekwini municiplaity's renaming of Umlazi's Mangosuthu Highway.
The ANC intends to honour renowned slain human rights lawyer Griffiths Mxenge by renaming it after him.
The IFP has called on the ANC provincial leadership to intervene in the matter.
The ANC-led eThekwini municipality indicated last month that it would forge ahead with its plans.
A ruling by the Durban high court in favour of the municipality in an interdict launched by both IFP and DA in the council paved the ANC's way.
Mxenge and his wife Victoria were killed by apartheid agents.
"We call on the ANC leadership in KwaZulu-Natal to instruct the eThekwini Metro council to halt this process. We still await closing unfinished political business between the IFP and ANC, dating back decades" IFP provincial secretary Bonginkosi Buthelezi said.
Buthelezi said this clash was just a symptom of a number of unfinished issues that the national leadership of both parties started on but left hanging.
He said the issues dated as far back as 1979, five years after the IFP was established.
"There have been attempts previously to have bilateral talks on a number of outstanding issues and until such matters are put to rest there will always be problems between the two organisations. The fact of the matter is that the IFP cannot wish the ANC away and the same applies to the ANC," Buthelezi said.
He said both parties suffered during the political violence that claimed more than 20 000 people and it was time for them to work towards the province's gain.
Attempts to get comment from the ANC drew a blank because provincial secretary Sihle Zikalala was not available. A woman answering his phone said he was in a meeting.