Santos' coach Bobbie Solomons believes it requires enough poise and character from a team to beat The Team of Choice in Cape Town.
"I strongly believe that it will be very difficult for other teams to beat us at home," he said Saturday night.
He was speaking after their 1-0 win over Mamelodi Sundowns in their Absa Premiership match at Newlands Stadium.
It was Santos' second win at this venue after defeating Ajax Cape Town 2-0 in the Mother City derby last Wednesday.
But they lost their first match of the season at this venue when they were beaten 1-0 by Bloemfontein Celtic on August 19.
Santos are second on the log with seven points from four matches, trailing log leaders Orlando Pirates by three points.
Downs' coach Hristo Stoichkov could not sit on the bench as he is serving suspension. His assistant Antoni-Lopez Conzalez took charge.
Santos grabbed the three points, thanks to Tyren Arendse's 27th minute goal that beat Sundowns' goalie Brian Baloyi.
Baloyi had parried Bonginkosi Macala's shot inside the box and Arendse was well-placed to drove it home.
But Stoichkov said he was happy with his side's general display on the night. However, he declined to comment when asked what action they will take against petulant forward Mabhuti Khenyeza for kicking Santos' goalkeeper Tshepo Motsoeneng.
Referee Harry Lekitlane duly sent Khenyeza off and he was booed on his way to the dressing room.