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The political careers of several Limpopo MECs who aligned themselves with former president Thabo Mbeki might well be over after this month's elections.
Acting premier Cassel Mathale, who is set to continue in the position after the election, is expected to order a cabinet clean-out.
Mathale is an avowed supporter of ANC president Jacob Zuma.
A senior ANC member told Sowetan that the "die-hard" Zuma supporters who stood by him long before the Polokwane conference, and who also supported Mathale in his provincial leadership battle with former premier Sello Moloto, were likely to form the new provincial cabinet.
The source said MECs such as Machueni Semenya of public works, Joyce Mashamba of sports arts and culture, Dikeledi Magadzi of agriculture, Seaparo Sekoati of health and social development, and Ratshivhanda Samson Ndou, of safety and security, were likely to be shown the door.
He said the new crop of cadres billed to fill their positions were current provincial secretary of the SACP, Soviet Lekganyane, ANCYL provincial chairman Lehlogonolo Masoga, deputy secretary of the ANC Pinky Kekana and treasurer Dipuo Letsatsi.
Reports that ANC Youth League president Julius Malema has written to Mathale's government suggesting that allies of the former premier holding top positions should be made to resign have also been read by many as a sign of things to come.
Moloto was a Mbeki ally who supported him during the ANC leadership tussle with Jacob Zuma. He has since joined the Cope, becoming its premiership candidate.
The source said deputy provincial chairman Namane Dickson Masemola, who is currently MEC in the premier's office and acting MEC for roads and transport, would be given the position of MEC for local government. Lekganyane is expected to head sports, arts and culture and Masoga is tipped to become the MEC for economic and development.
Professor Lesiba Tefo, a political analyst from the University of Limpopo, said the new cabinet would be drawn from the top five leaders of the ANC provincial executive committee, the ANCYL and the South African Communist Party.
He said Mathale would have an easy run for the premiership because possible contenders such as Maite Nkoana Mashabane of local government and housing were expected to go to national government posts.