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'Risky' TB drugs recalled after tests

By unknown | Aug 12, 2008 | COMMENTS [ 0 ]

Zinhle Mapumulo

Zinhle Mapumulo

Two other life-saving drugs meant to cure TB are being recalled by the Health Department.

The department said yesterday it was investigating the quality and stability of two tuberculosis drugs, Antib-4 and EBSAR, made by Pharmascript.

Tests showed levels of key ingredients in the two drugs were too low, and could be placing patients at risk by not receiving their required dosage.

Antib-4, four-in-one combination, and EBSAR, two-in-one combination, are used to treat TB that is not multi or extreme resistant.

Health Minister Manto Tshabalala-Msimang expressed concern about the findings. "[We] received information suggesting the ingredients in AntibB-4 and EBSAR were not at the level stated on the label after storage.

"Investigations conducted over three months at the North West University found that the drugs that had been on the shelves for six months complied with the levels claimed," she said.

But, the results of a further three-month stability test on the same batch indicated that in the ANTIB-4, at least two of the four ingredients were below the level claimed. Both EBSAR ingredients were below the required level.


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